Marcos

It can be disabled via a policy. If you are not seeing these settings, please post a screenshot of installed modules (Help -> About):

Does clearing Bridge cache make a difference? https://help.eset.com/ebe/2/en-US/?troubleshooting.html

Cleaner module 1245 is already available on the pre-release update channel.

Please uninstall ESET 16.2 and install the latest v16.2.15 from scratch with default settings. Then switch the firewall to interactive mode and create rules. If you can reproduce the issue, provide step-by-step instructions how to reproduce it. Also please raise a support ticket so that the case is properly tracked in the ticketing system.

This issue will be fixed via an automatic module update within 1-2 weeks. As a workaround, please unselect the registry in scan target selection.

Thanks for the heads-up. I was able to reproduce it by following your instructions and reported it to developers with higher priority.
P_EESW-10933

Release Date: October 30, 2023
ESET CyberSecurity for macOS 7.4.1600.0 has been released and is available to download.
Changelog:
Version 7.4.1600.0
FIXED: The product sometimes loses Full Disk Access after OS restart
FIXED: PCU update during an OS restart no longer breaks the product
FIXED: Web access protection issues after upgrade from version 6
FIXED: Services are not connected sometimes after upgrade from an older product
Known issues
Previous versions v7.1 and 7.2 incorrectly migrates TSN RTP settings from V6. If you have upgraded from v6 to the previous v7.1 or 7.2, we highly recommend installing v7.4, opening the RTP TSN 'For all file operations' settings and turning off Advanced heuristic. This setting was incorrectly enabled during migration from v6. The Onboarding wizard is shown after silent installation.
Full disk access is lost after a macOS Sonoma restart. This is a macOS issue that Apple is aware of and will probably fix it in one of the upcoming minor macOS releases. A workaround was added to v7.4 which prevents FDA from getting lost on real hardware (it may still get lost in virtual environments). Upgrade to Latest Version
Upgrade my ESET CyberSecurity for macOS to the latest version
 
Support Resources
ESET provides support in the form of Online Help (user guides), fully localized application and Online Help, online Knowledgebase, and applicable to your region, chat, email or phone support.
Online Help (user guides) Visit www.eset.com/contact to email ESET technical support

Release Date: October 30, 2023
ESET Endpoint Antivirus for macOS 7.4.1500.0 has been released. The current version is available only for managed environments from the ESET repository. ESET Endpoint Security will be released later.
Changelog:
Version 7.4.1500.0
Fixed: The product sometimes loses FDA after OS restart
Fixed: PCU update during an OS restart no longer breaks the product
Fixed: Web access protection issues after upgrade from version
Known issues
Previous versions v7.1 and 7.2 incorrectly migrates TSN RTP settings from V6. If you have upgraded from v6 to the previous v7.1 or 7.2, we highly recommend installing v7.4, opening the RTP TSN 'For all file operations' settings and turning off Advanced heuristic. This setting was incorrectly enabled during migration from v6. The Onboarding wizard is shown after silent installation. 
For a workaround, follow the instructions available at the ESET KB:
https://support.eset.com/en/kb8506-onboarding-wizard-displayed-during-a-remote-installation-of-eset-endpoint-antivirus-for-macos
https://support.eset.com/en/kb6927-known-issues-for-latest-versions-eset-business-products
Full disk access is lost after a macOS Sonoma restart. This is a macOS issue that Apple is aware of and will probably fix it in one of the upcoming minor macOS releases. A workaround was added to v7.4 which prevents FDA from getting lost on real hardware (it may still get lost in virtual environments). Support Resources
ESET provides support in the form of Online Help (user guides), fully localized application and Online Help, online Knowledgebase, and applicable to your region, chat, email or phone support.
Online Help (user guides) Visit www.eset.com/contact to email ESET technical support

Please do not select the registry as a scan target until a new version of the Cleaner module is released (ETA is 1 week to the  release on the pre-release update channel). Otherwise it may take hours for the scan to complete.

Please refer to https://support.eset.com/en/kb6567 for more information and instructions how to create a detection exclusion if upgrading the motherboard firmware doesn't help or it's not an option.
Also if you search for CompuTrace in this forum you'll find many topics on the subject.

Yes, we have pinpointed it to the Cleaner module, in particular, to recent changes in the registry value parser which ineffectively parses certain registry values with many tokens and that unnecessarily prolongs the scan time. We expect a new version of the Cleaner module addressing this issue to be available on the pre-release update channel in approximately 1 week. Also I'd like to mention not to pay much attention to the file displayed in the scanner window as it's the last file that was successfully scanned.

Does pressing Ctrl+F5 make a difference? If not, carry on as follows:
Close the browser. Enable advanced logging under Help and support -> Technical support Launch the browser and reproduce the issue Stop logging Collect logs with ESET Log Collector and upload the generated archive here.

Support for Thunderbird was discontinued years ago. However, email received via IMAP(S) or POP3(S) in Thunderbird is scanned by ESET. It's just that you can't scan already received messsages on demand or that received messages are not scanned by ESET antispam. Otherwise malware should be normally detected in received email.

Please provide logs that you collected with ESET Log Collector after generating an advanced OS log EsetPerf.etl.

It will be updated with latest information within today or tomorrow at latest.

Support for Thunderbird was discontinued years ago. However, email received via IMAP(S) or POP3(S) in Thunderbird is scanned by ESET. It's just that you can't scan already received messsages on demand or that received messages are not scanned by ESET antispam. Otherwise malware should be normally detected in received email.

V6 is in limited support and as such is not developed any more:
https://support-eol.eset.com/en/policy_business/product_tables.html
V7 with added features will be available in the future.

V6 is in limited support and as such is not developed any more:
https://support-eol.eset.com/en/policy_business/product_tables.html
V7 with added features will be available in the future.

There are currently no plans to release EEA v6 compatible with macOS Sonoma. However, you can contact your local ESET distributor or reseller and they'll try to come up with a solution for you.

Unfortunately without knowing the detection name and the object where the detection was triggered we can't help you and give some suggestions. I can only assume those are HIPS-based behavioral on in-memory detections which can be disabled only in the advanced setup and not via the tray icon menu.

Support for Thunderbird was discontinued years ago. However, email received via IMAP(S) or POP3(S) in Thunderbird is scanned by ESET. It's just that you can't scan already received messsages on demand or that received messages are not scanned by ESET antispam. Otherwise malware should be normally detected in received email.

On the second machine you had Secure all browsers (SAB) disabled and set up some protected websites in the past. Later you enabled SAB.

We don't check for installed updates but perform a true ACS test instead. This information is from the developer who implemented the test routine that creates the said registry value.

Please use the latest version of Process Explorer from the Microsoft website.

The latest version does not contain a vulnerable driver.