There should be no negative impact in case latency to ESLC is in acceptable numbers.
Unfortunately, it's not possible to say how much impact did Cache brought to you. All connected endpoints did 160.000 requests to Cache for the result, however, it's not clear how many of them received a valid result of a scan. In case you've same files which are not whitelisted, it could bring benefit. However, it might happen that there are stored scan results of files which don't exist on other computers, so these results did not provide any benefit to other computers.