This has happened twice recently. The last was last night. Server stopped doing anything (except responding to ping). I had to do a hard reset.
The last entries in the msglog are all ESET related and there are hundreds like this (all different file names):
kernel: eset_rtp: wait for scanner reply timeout, path: /usr/lib64/sasl2/smtpd.conf, event: OPEN, pid: 692
The messages started at 21:17 and stopped at 22:29 with only eset_rtp messages in this time frame, then the next message is when I hard-reset the server this morning. The error message occurred 33318 times.