I have rolled back Windows 10 RS5 to RS4 on my main desktop PC. Both Firefox and Thunderbird now work fine on that machine, without the exclusions that I had needed to set up for these programs in NOD32's Protocol Filtering.
As an aside : on my work laptop, Windows 10 RS5 had completely wrecked any audio functionality. Rolling the laptop back to RS4 restored that (fortunately, its Thunderbird's functionality had not been affected).
Don't you just LOVE Micro$oft... IMHO they have really shot themselves in the foot with this "Creators Update", but since their systems are so widespread I would suspect that they will just be able to shrug it off and get away with it ?