I have exactly same problem with ESET Endpoint Security on Mojave 10.14.1. If ESET is installed, you can not add new applications to the "Accessibility" menu. If I try, all items will disappear and nothing will be saved.
If I uninstall ESET, it seems that everything works again.
I think it is bug and I hope that ESET will fix it soon.
[UPDATE: Fixed in 6.7.400] Cyber Security is Blocking my system's Accessibility Features in Security and Privacy
in ESET Cyber Security Pro (for Mac)
Posted
Hello,
I have exactly same problem with ESET Endpoint Security on Mojave 10.14.1. If ESET is installed, you can not add new applications to the "Accessibility" menu. If I try, all items will disappear and nothing will be saved.
If I uninstall ESET, it seems that everything works again.
I think it is bug and I hope that ESET will fix it soon.