Can I and Should I use YubiKey with ESET Password Manager?

[Havokry 0]

I just got a YubiKey and I don't know the best means to use it yet. I still have to figure out if I want to switch to a local account to use it for my windows laptop. I would like to use it where I am required to enter a 8 character password at most with required yubikey insertion. 

[Marcos 5,733]

Unfortunately I don't have such USB key to test but maybe somebody else will be able to tell.