Yes. After that - reboot system and your icons positions will be restored to correct EA 5.0.2237.1 has also picked up the Cleaner module 1114 (the released version, not pre-release) yesterday. And it fixes the problem as well. The registry keys now stay what they are supposed to be on Windows 10.
I'm using ESET Endpoint Antivirus version 5.0.2237.1, Cleaner module 1113. It is compatible with Windows 10 according your website: hxxp://support.eset.com/kb3747/ The problem still exists.