I'm getting the same pop-up since I upgraded to windows 10. It happens a lot when I switch between windows using alt-tab. I have confirmed that it pops up when ESET switches to gamer mode. I don't use Edge so it is either not related to Edge or Edge doesn't need to be open for it to occur. I see it when I switch between LibreOffice Calc windows or Chrome windows. Those applications are what I use the most and haven't had time to test it with other apps.
Turning off "Setup->Enter Advanced Setup->Computer->Gamer mode->Enable Gamer mode when running applications in full-screen automatically" does get rid of the warning. However, this is merely a workaround.
There is an advanced setting "User interface->Alerts and notifications->Desktop notifications->Do not display notifications when running applications in full-screen mode". If this setting is checked (as it is in my config) these notifications should not pop-up.
It is clear from the appearance of this pop-up that it is not generated the same way that other notifications are generated (see sample notification attached) so it may not be governed by this setting. It appears that it is generated by the OS based on information the software is sending to it.
In this case the application should be changed so that the message is either not generated as frequently, is otherwise hideable, or is governed by this setting.
