Not sure if it's a factor, but my KeePass program is installed on "D:\Program Files\KeePass" . I install the portable version from the zip file, rather than using the windows installer. I'm mentioning this just in case the location of the exe might influence NOD32's behaviour.
I've attached video of the problem. Excuse the quality, but screen recording won't work with switching desktops, so I had to use my phone. I try to open the database 3 times - first with NOD32 fully functional and it bugs, then with gamer mode ON and its OK, then back to gamer mode OFF and it bugs.
KP-NOD32.mp4