Hi
Not for me it hasn't...
I am running;
ESET Endpoint Security 9.1.2060.0
Microsoft® Outlook® for Microsoft 365 MSO (Version 2210 Build 16.0.15726.20070) 64-bit
If I have "Integrate into Microsoft Outlook" enabled it appears to work, but if I then "Enable email client antispam", Outlook stops responding.
Phil