With Windows PE
You can boot from any x64 pc where as sysrescue you are entirely dependent on the CSM.
You can unlock bitlocker encrypted drives so the contents can be scanned.
Both of the above are show stoppers not annoyances.
I understand the convenience argument but this toy designed for consumers is now being flogged to enterprise users who will probably already have the AIK installed aswell as the SDK, RSAT etc etc etc.
Its not fit for business.
The only alternative ive found is to use Windows To Go which isn't cheap.
Most, Not all and those that don't wont work with sysrescue live and would with a Windows PE based image.
Some have no option but Secure Boot. its all up to the vendor.