I only have installed the NOD32 version 8 Antivirus; not Smart Security.
The original post and mine appear to involve debugging a web app running under IIS on the development machine with Visual Studio. Is there an issue with NOD32 and IIS?
I too resolved the issue by uninstalling NOD32 version 8 and reinstalling NOD32 version 7. Since we're an ISV, I don't have the luxury of having 8 installed while I'm out of business and not able to debug one of our web apps. I'd like to try the exclusion setting but 7 does/did not require it ... so it is in the code changes between 7 and 8.
Ron