I've been having the same issue with Eset Cyber Security 6.8.300.0 caused by the esets_proxy process hanging / using 190-300% CPU and causing most applications like Excel, Word, 1Password and so on to launch in 60+ seconds!
This week my Windows 10 VM running under VMware Fusion 11.5.5 hanged twice completely along with the entire MacBook Pro system, if can believe this! Running Catalina 10.15.6 here on a MacBook Pro 2018.
I tried to open a support ticket, but I did not receive any e-mail confirmation after sending the info.
I have attached here the info collected with the Log C