FOR MAC USERS: After searching and searching for a solution to why my Dropbox was giving me the error "can't establish secure internet connection", (and after talking to Dropbox support), and after finally getting to chat with an ESET tech support person, the following solution worked.
Open ESET Cyber Security preferences, click "Web Access Protection" and UNCHECK "Enable HTTP protocol checking".
ALSO, go to "General", "Exclusions: Setup...", under "File System" click the plus sign and find your Dropbox application in your Applications folder to add in the list. THEN, also click "Web and Email", then under "Display exclusions:" go to "Applications" and also add the Dropbox application there. Click "OK". Both might not be necessary, but that's what got Dropbox connecting and synching again for me.