Add option to realtime scanner to block obfuscated Powershell scripts. Option would be dependent upon Win 10 AMSI option enabled in the Eset GUI.
Microsoft added a like mitigation in the form of a Windows Defender Exploit Guard ASR mitigation effective with Win 10 1709. ASR mitigations are only effective if Windows Defender is enabled as the realtime scan engine.
Further justification is Eset's failure to detect malware in highly obfuscated PowerShell script in a Malware Research Group ad hoc test: https://www.mrg-effitas.com/research/current-state-of-malicious-powershell-script-blocking/